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Critical Mutation
Warframe · Mod

Critical Mutation

Catabolyst kill-stacking augment

Released Oct 18, 2023

Critical Mutation is a Catabolyst-specific augment that builds critical chance and critical damage from kills, up to 300%, while grenade explosions that strike fewer than three enemies reduce the bonuses. Consider it when you can maintain kills and reliably hit groups with the grenade explosion.

TypeCatabolystPolaritymaduraiMax rank5Base drain2VariantStandardRarityRare
Critical Mutation GUIDE

Understand Critical Mutation

Useful when…

  • Build up both critical stats through kills while using the Catabolyst.
  • Use the grenade explosion against at least three enemies to avoid the stated reduction.

How does the stacking effect work?

Each kill increases both critical chance and critical damage. At rank 0, each kill adds 5%; at rank 3 it adds 20%; at rank 5 it adds 30%, with a 300% cap. The augment's description does not specify a separate duration for the accumulated bonus, so do not assume a timed decay.

wiki.warframe.com ↗

What causes the reduction?

If the grenade explosion strikes fewer than three enemies, the bonus is reduced by 5% at rank 0, 20% at rank 3, or 30% at rank 5. That condition makes the augment less reliable when explosions hit isolated targets. The Catabolyst restriction is explicit; the mod is not described as compatible with other pistols.

wiki.warframe.com ↗

How much to fuse?

It reaches rank 5. Higher ranks increase the per-kill gain and the reduction triggered by explosions hitting fewer than three enemies, while the cap remains 300%. The final step from rank 4 to 5 costs 480 Endo and 23,184 Credits. Weigh the stronger per-kill change against the matching larger penalty when the grenade hits too few targets.

wiki.warframe.com ↗

Limitations and tradeoffs

  • The bonus depends on kill accumulation and is reduced by grenade explosions hitting fewer than three enemies.
  • The per-kill increase and the reduction both grow with rank.

Common mistakes to avoid

  • Assuming grenade explosions against one or two enemies preserve the accumulated bonus.
  • Treating the 300% cap as the amount gained per kill instead of the maximum.

Effects and reference details

Rank effects and investment

RankListed effectsUnpolarized drainTotal Endo from rank 0Total Credits from rank 0
0Each kill increases Critical Chance and Critical Damage by 5% up to 300%. Reduce by 5% when fewer than 3 enemies are struck by the grenade explosion.200
1Each kill increases Critical Chance and Critical Damage by 10% up to 300%. Reduce by 10% when fewer than 3 enemies are struck by the grenade explosion.3301,449
2Each kill increases Critical Chance and Critical Damage by 15% up to 300%. Reduce by 15% when fewer than 3 enemies are struck by the grenade explosion.4904,347
3Each kill increases Critical Chance and Critical Damage by 20% up to 300%. Reduce by 20% when fewer than 3 enemies are struck by the grenade explosion.521010,143
4Each kill increases Critical Chance and Critical Damage by 25% up to 300%. Reduce by 25% when fewer than 3 enemies are struck by the grenade explosion.645021,735
5Each kill increases Critical Chance and Critical Damage by 30% up to 300%. Reduce by 30% when fewer than 3 enemies are struck by the grenade explosion.793044,919

These are listed mod effects and fusion costs, not final build damage. Matching and mismatched polarities change capacity. Totals assume starting at rank 0.

References and version

Game data version: Pinned public export

Critical Mutation — WARFRAME Wiki ↗wiki.warframe.com ↗
Technical source data for verification

These machine-readable game records support the calculations and factual checks. The wiki references above are intended for reading.

wiki.warframe.com ↗Warframe Public Export ↗

Original data record ↗

Optional: calculate an upgrade or configurationOpen the calculator when you want a cost estimate or a compatibility check.
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Fusion cost and capacity

0Endo
0Credits
2Target slot drain
RankObserved effectDrainEndo from 0Credits from 0
0Each kill increases Critical Chance and Critical Damage by 5% up to 300%. Reduce by 5% when fewer than 3 enemies are struck by the grenade explosion.200
1Each kill increases Critical Chance and Critical Damage by 10% up to 300%. Reduce by 10% when fewer than 3 enemies are struck by the grenade explosion.3301,449
2Each kill increases Critical Chance and Critical Damage by 15% up to 300%. Reduce by 15% when fewer than 3 enemies are struck by the grenade explosion.4904,347
3Each kill increases Critical Chance and Critical Damage by 20% up to 300%. Reduce by 20% when fewer than 3 enemies are struck by the grenade explosion.521010,143
4Each kill increases Critical Chance and Critical Damage by 25% up to 300%. Reduce by 25% when fewer than 3 enemies are struck by the grenade explosion.645021,735
5Each kill increases Critical Chance and Critical Damage by 30% up to 300%. Reduce by 30% when fewer than 3 enemies are struck by the grenade explosion.793044,919

Slot polarity changes drain; fusion prices depend on mod rarity and family.

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