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Nidus Prime
Warframe · Warframe

Nidus Prime

Nidus Prime is a high-health Warframe whose abilities group enemies and interact through Mutation, with Parasitic Link offering a conditional ally or enemy effect.

Released Sep 8, 2021

Consider Nidus Prime when you want to build and use Mutation through repeated ability interactions. He has 825 Health, 425 Armor, and no Shields; his kit groups enemies, gains energy through Virulence, and links to an ally or enemy with different effects.

TypeWarframeMastery requirement0Armor425Health825Shield0
Nidus Prime GUIDE

Understand Nidus Prime

Useful when…

  • Strike groups with Virulence to damage enemies and gain energy from each enemy hit; hitting every five enemies increases its destructive force.
  • Use Larva to pull nearby enemies together; kills while enemies are held have a chance to generate Mutation.
  • Cast Parasitic Link on an ally to increase both characters’ Ability Strength and Weapon Damage, or on an enemy so it takes some of the damage inflicted on Nidus.
  • Use Virulence to hit Ravenous maggots so they burst with Infestation.

Ability effects and interactions

Virulence ruptures the ground with a damaging fungal growth and steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates and multiplies its destructive force. Larva’s pod pulls nearby enemies in with tendrils; enemies killed while held have a chance of generating a Mutation stack. Parasitic Link has two distinct uses: cast on an ally to increase Ability Strength and Weapon Damage for both host and Nidus, or cast on an enemy so it takes some of the damage inflicted on Nidus. Ravenous sends maggots against nearby enemies; the maggots benefit from Mutation and add to the Mutation stack when they hit. They burst with Infestation when struck by Virulence.

Survival and passive

Nidus Prime’s listed defenses are 825 Health, 425 Armor, and zero Shields. His passive describes a recovery if he is killed with at least a specified number of Mutation stacks: those stacks are consumed, granting a period of invulnerability and restoring Health. The threshold, duration, and restored percentage are unresolved in the supplied description, so treat the passive as conditional protection rather than relying on a specific numerical value.

Using Mutation deliberately

Larva’s kills generate Mutation only with a chance, while Virulence’s destructive-force increase is tied to hitting groups of five enemies. Ravenous contributes Mutation when its maggots hit, and Virulence can trigger their burst effect. These are related but separate conditions: a Larva kill, a five-enemy Virulence hit, and a maggot hit do not have interchangeable effects. Grouping enemies with Larva can make a clustered target for area abilities, while the exact amount of Mutation gained is not specified here.

Comparison and investment

Compared with the Nidus entry, Nidus Prime lists 825 rather than 675 Health and 425 rather than 350 Armor; both list zero Shields. The comparison does not provide Nidus’s ability details or polarities, so it does not establish that their abilities or configurations match. Voruna and Voruna Prime are described in terms of a wolf pack, strength, and stealth, rather than Nidus Prime’s documented Mutation interactions. Consider Nidus Prime for his listed kit and defenses; the available comparisons do not establish a universal priority or direct mechanical substitute.

Limitations and tradeoffs

  • Several effects depend on conditions: Larva kills only have a chance to generate Mutation, and Virulence’s destructive-force increase is tied to hitting five enemies.
  • Nidus Prime has no Shields; his listed defenses are Health and Armor.
  • The passive’s Mutation threshold and numerical recovery benefits are unspecified.

Common mistakes to avoid

  • Expecting every enemy killed while held by Larva to generate Mutation.
  • Confusing Virulence’s every-five-enemies destructive-force increase with other Mutation gains.
  • Assuming Nidus Prime has Shields or treating the passive’s unresolved values as fixed numbers.
  • Using Parasitic Link as though its ally and enemy targeting modes had the same effect.

Effects and reference details

Detailed properties

Listed health825
Listed shields0
Listed armor425
Energy140
Sprint speed1
Foundry Credits25,000
Foundry time72 hours
Virulence

Rupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.

Larva

Spawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.

Parasitic Link

Bind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength and Weapon Damage increased. Linked enemies take some of the damage inflicted on Nidus.

Ravenous

Gluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.

References and version

Game data version: Pinned public export

Nidus Prime — WARFRAME Wiki ↗
Technical source data for verification

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Mod capacity and investment

Unranked base capacity: 15 + one per two Mastery Ranks through MR30. Legendary ranks add one each. Rank-40 equipment unlocks two extra ranks per installed Forma.

Aura slots

Aura 1

Eight standard slots

Slot 1
Slot 2
Slot 3
Slot 4
Slot 5
Slot 6
Slot 7
Slot 8
0Drain
30Capacity
30Remaining

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